** BANNER **
** BANNER END **
** MAIN **
** MAIN END **
** ADV **
- 대용량 변이 탐색(SNPs, INDEL, SV)
- 변이 기능분석(cSNP, intergenic SNPs, synonymous/non-synonymous SNPs, etc.)
- 집단분석(STRUCTURE, Phylogeny, FST, Pi, IBS, LD)
- 유전형-표현형 연관분석(GWAS, Heterozygosity, ROD)
- QTL 분석
** ADV END **
** FUNCTION **
주요 기능 소개
** FUNCTION IMG TABLE **
집단 분석
- Phylogeny tree : SNP 정보를 활용한 개체 별 유연관계
- PCA plot : 주성분 분석을 통한 개체 간 유전적 유사성
- LD decay plot : 개체 간 변이 변화율의 유전적 수렴도
- Genetic structure : 집단 내 개체들의 유전적 구조
- IBS : 개체 간 직접적인 유전적 유사도
- FST : 집단 간 유전적 유사도(표현형1 vs 표현형2)
유전형-표현형 연관분석
- GWAS(Genome wide association study)
- Heterozygosity
- ROD(Reduction of Diversity)
- QTL 탐색
- 표현형 원인 유전자 탐색
** FUNCTION IMG TABLE END **
** FUNCTION END **
** RESEARCH-Ex **
적용 사례
incoVARIATION이 연구에서 어떤 역할을 하는지 확인해보세요.
Article
-
Heo S, Cho S, Dinh PTN, Park J, Jin DH, Cha J, Kim YK, Koh YJ, Lee SH, Lee JH. A genome-wide association study for eumelanin pigmentation in chicken plumage using a computer vision approach. Anim Genet. 2023 Jun;54(3):355-362. doi: 10.1111/age.13303. Epub 2023 Mar 1. PMID: 36855963.
-
Kim M, Cho E, Munyaneza JP, Ediriweera TK, Cha J, Jin D, Cho S, Lee JH. Genome-wide association study for the free amino acid and nucleotide components of breast meat in an F2 crossbred chicken population. J Anim Sci Technol. 2023 Jan;65(1):57-68. doi: 10.5187/jast.2022.e96. Epub 2023 Jan 31. PMID: 37093927; PMCID: PMC10119464.
-
Cho E, Cho S, Kim M, Ediriweera TK, Seo D, Lee SS, Cha J, Jin D, Kim YK, Lee JH. Single nucleotide polymorphism marker combinations for classifying Yeonsan Ogye chicken using a machine learning approach. J Anim Sci Technol. 2022 Sep;64(5):830-841. doi: 10.5187/jast.2022.e64. Epub 2022 Sep 30. PMID: 36287747; PMCID: PMC9574617.
-
Lee C, Cheon KS, Shin Y, Oh H, Jeong YM, Jang H, Park YC, Kim KY, Cho HC, Won YJ, Baek J, Cha YS, Kim SL, Kim KH, Ji H. Development and Application of a Target Capture Sequencing SNP-Genotyping Platform in Rice. Genes (Basel). 2022 Apr 28;13(5):794. doi: 10.3390/genes13050794. PMID: 35627177; PMCID: PMC9141132.
-
Yu GE, Shin Y, Subramaniyam S, Kang SH, Lee SM, Cho C, Lee SS, Kim CK. Machine learning, transcriptome, and genotyping chip analyses provide insights into SNP markers identifying flower color in Platycodon grandiflorus. Sci Rep. 2021 Apr 13;11(1):8019. doi: 10.1038/s41598-021-87281-0. PMID: 33850210; PMCID: PMC8044237.
-
Kang MJ, Shin AY, Shin Y, Lee SA, Lee HR, Kim TD, Choi M, Koo N, Kim YM, Kyeong D, Subramaniyam S, Park EJ. Identification of transcriptome-wide, nut weight-associated SNPs in Castanea crenata. Sci Rep. 2019 Sep 11;9(1):13161. doi: 10.1038/s41598-019-49618-8. PMID: 31511588; PMCID: PMC6739505.
-
Nam BH, Yoo D, Kim YO, Park JY, Shin Y, Shin GH, Park CI, Kim H, Kwak W. Whole genome sequencing reveals the impact of recent artificial selection on red sea bream reared in fish farms. Sci Rep. 2019 Apr 24;9(1):6487. doi: 10.1038/s41598-019-42988-z. Erratum in: Sci Rep. 2020 Jan 28;10(1):1625. PMID: 31019228; PMCID: PMC6482192.
-
Oh JH, Lee YJ, Byeon EJ, Kang BC, Kyeoung DS, Kim CK. Whole-genome resequencing and transcriptomic analysis of genes regulating anthocyanin biosynthesis in black rice plants. 3 Biotech. 2018 Feb;8(2):115. doi: 10.1007/s13205-018-1140-3. Epub 2018 Feb 7. PMID: 29430376; PMCID: PMC5801106.
-
Seol YJ, Won SY, Shin Y, Lee JY, Chun JS, Kim YK, Kim CK. A Multilayered Screening Method for the Identification of Regulatory Genes in Rice by Agronomic Traits. Evol Bioinform Online. 2016 Nov 2;12:253-262. doi: 10.4137/EBO.S40622. PMID: 27840573; PMCID: PMC5094579.
-
Shin Y, Jung HJ, Jung M, Yoo S, Subramaniyam S, Markkandan K, Kang JM, Rai R, Park J, Kim JJ. Discovery of Gene Sources for Economic Traits in Hanwoo by Whole-genome Resequencing. Asian-Australas J Anim Sci. 2016 Sep;29(9):1353-62. doi: 10.5713/ajas.15.0760. Epub 2016 Mar 4. PMID: 26954201; PMCID: PMC5003998.
-
Lim D, Kim HY, Cho YM, Chai HH, Park JE, Lim KS, Lee SS. Construction of gene network system associated with economic traits in cattle. J Lif Sci. 2016 Aug 23;26(8):04-910. doi: 10.5353/JLS.2016.26.8.904
-
Kim CK, Seol YJ, Shin Y, Lim HM, Lee GS, Kim AR, Lee TH, Lee JH, Park DS, Yoo S, Kim YH, Kim YK. Whole-genome resequencing and transcriptomic analysis to identify genes involved in leaf-color diversity in ornamental rice plants. PLoS One. 2015 Apr 21;10(4):e0124071. doi: 10.1371/journal.pone.0124071. PMID: 25897514; PMCID: PMC4405343.
-
Seo DW, Oh JD, Jin S, Song KD, Park HB, Heo KN, Shin Y, Jung M, Park J, Jo C, Lee HK, Lee JH. Single nucleotide polymorphism analysis of Korean native chickens using next generation sequencing data. Mol Biol Rep. 2015 Feb;42(2):471-7. doi: 10.1007/s11033-014-3790-5. Epub 2014 Oct 11. Erratum in: Mol Biol Rep. 2015 Feb;42(2):567. PMID: 25304812.